Calbiotech

C-Reactive Protein ELISA

Name: C-Reactive Protein ELISA
Brand: Calbiotech
SKU: CR375C
Price: 350.00 USD
Availability: InStock

In stock

SKU: CR375C

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$350.00

SUMMARY AND EXPLANATION:

C-Reactive protein (CRP) is an alpha globulin with a molecular mass of approximately 110,000 to 140,000 daltons, and is composed of five identical subunits, which are noncovalently assembled as a cyclic pentamer. CRP is an acute-phase protein synthesized by the liver in response to cytokines such as IL-6. Research uses include inflammatory signaling pathways, acute-phase reactant kinetics, and the role of CRP in host–pathogen and host–injury responses.

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Catalog number	CR120C
Product type	ELISA
Quantity	96 Tests (12x8 breakable strip wells)
Standard range	0.005-0.1 mg/L
Analytical Sensitivity	0.005 mg/L
Sample volume	10 µl/well
Species	Human
Storage and Stability	Product should be stored at 2-8 °C.
Precautions	For research use only. Not for use in diagnostic procedures.
References	1. Schultz, D.R., and Arnold P.I.: “Properties of four acute phase proteins: C-reactive protein, serum amyloid A protein, glycoprotein, and fibrinogen.” Seminars in Arthritis and Rheumatism 20: 129-147, 1990. 2. Kindmark, C.O.: The Concentration of C-reactive protein in Sera from Healthy Individuals. Scand J Clin Lab Invest, 29: 407- 411, 1972. 3. Dowling, P., and Cook, S.: Immune events in demyelinating disease. In Wolfgang, F., Ellison, G.W., Stevens J.G., and Andrew, J.M. (eds.): Multiple sclerosis. Academic Press Inc., New York, 269-277, 1972. 4. YUDKIN, J.S., ET. AL.: C-REACTIVE PROTEIN IN HEALTHY SUBJECTS: ASSOCIATION WITH OBESITY, INSULIN RESISTANCE, AND ENDOTHELIAL DYSFUNCTION. A POTENTIAL ROLE FOR CYTOKINES ORIGINATING FROM ADIPOSE TISSUE? ARTERIOSCLER THROMB VASC BIOL 19:972-8, 1999. 5. Kushner, I., Rzewnicki, D.L.: The acute phase response: General aspects. Bailliere’s Clinical Rheumatology 8: 513-530, 1994. 6. Macy, E.M., Hayes, T.E., and Tracy, R.P.: Variability in the measurement of C-reactive protein in healthy subjects: implications for reference interval and epidemiological applications. Clin Chem, 43;1:52-58, 1997. 7. Hedlund, P.: Clinical and experimental studies on C-reactive protein (acute phase protein). Thesis Acta Med Scand, 128 (Suppl, 361):1-71, 1961. 8. Hedlund, P.: The appearance of acute phase protein in various diseases. Acta Med Scand, 128, (Suppl,196): 579-601, 1947. 9. Morley, J.J., Kushner, I.: Serum C-reactive Protein Levels. in: Kushner, I., Volanakis, J.E., and Gerwutz, H., eds., C-Reactive Protein and the Plasma Protein Response to Tissue Injury. Annals of N.Y. Acad Sci, 389: 406-417, 1982.