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Calbiotech

Dengue Virus IgM ELISA

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SKU: DE051M
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$350.00

SUMMARY AND EXPLANATION:

Dengue virus (DENV), a flavivirus transmitted by Aedes mosquitoes, consists of four antigenically distinct serotypes (DENV-1 to DENV-4). Primary infection can result in a spectrum of disease outcomes, from mild febrile illness to severe forms such as dengue hemorrhagic fever. The IgM antibody response emerges within days after symptom onset, peaks within several weeks, and then declines over months. The kinetics of IgM production differ between primary and secondary infections, making it a focal point for research on immune enhancement phenomena such as antibody-dependent enhancement (ADE). Studies of IgM dynamics help researchers examine viral epidemiology, outbreak timing, and immune response modulation.

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United States: For Research Use Only. For professional use only. Not for use in diagnostic procedures.

International Markets: For Export Only. For professional use only. Use subject to applicable regulations in the destination country.
Catalog number
 DE051M
Product type ELISA
Quantity
 96 Tests (12x8 breakable strip wells)
Sample volume 10 µl/well
Species Human
Storage and Stability Product should be stored at 2-8 °C. 
Precautions For research use only. Not for use in diagnostic procedures.
References 1. Pinheiro FP, Corber SJ: Global situation of dengue and dengue haemorrhagic fever, and its emergence in the Americas. World Health Stat Q 50(3/4):161-169, 1997.
2. Gubler DJ, Trent DW: Emergence of epidemic dengue/dengue hemorrhagic fever as a public health problem in the Americas. Infect Agents Dis 2:383-393, 1993.
3. Wu SJ; Hanson B; Paxton H; Nisalak A; Vaughn DW; Rossi C; Henchal EA; Porter KR; Watts DM; Hayes CG. Evaluation of a dipstick enzyme-linked immunosorbent assay for detection of antibodies to dengue virus.
Clin Diagn Lab Immunol1997; 4(4):452-7.
4. Lam SK; Devine PL. Evaluation of capture ELISA and rapid immunochromatographic test for the determination of IgM and IgG antibodies produced during dengue infection. Clin Diagn Virol 1998;10(1):75-8.
5. Rossi CA; Drabick JJ; Gambel JM; Sun W; Lewis TE; Henchal EA. Laboratory diagnosis of acute dengue fever during the United Nations Mission in Haiti, 1995-1996. Am J Trop Med Hyg 1998;59(2):275-8

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  • SKU DE051M