Calbiotech

Free Prostate Specific Antigen (f-PSA) ELISA

Name: Free Prostate Specific Antigen (f-PSA) ELISA
Brand: Calbiotech
SKU: PS233T
Price: 350.00 USD
Availability: InStock

In stock

SKU: PS233T

(0)

$350.00

SUMMARY AND EXPLANATION:

Human Prostate Specific Antigen (PSA) is a 33 kD serine proteinase which, in human serum, is predominantly bound to alpha 1-antichymotrypsin (PSA-ACT) and alpha 2-macroglobulin (PSAAMG). Trace amounts of alpha 1-antitrypsin and inter-alpha trypsin inhibitor bound to PSA can also be found. Any remaining PSA is in the free form (f-PSA). This product measures the unbound (free) fraction of PSA in serum or plasma. In research, f-PSA is used to study molecular forms of PSA, evaluate proteolytic processing, and investigate androgen-regulated protein expression. It is also useful for protein interaction studies and biomarker ratio analysis in preclinical models.

Got questions?

Feel free to get in touch

Catalog number	PS233T
Product type	ELISA
Quantity	96 Tests (12x8 breakable strip wells)
Standard range	1-25 ng/ml
Analytical Sensitivity	1 ng/ml
Sample volume	50 µl/well
Species	Human
Storage and Stability	Product should be stored at 2-8 °C.
Precautions	For research use only. Not for use in diagnostic procedures.
References	1. Christensson A, Bjork T, Nilsson O, et al. Serum Prostate Specific Antigen Complexed to a1-Antichymotrypsin As An Indicator of Prostate Cancer. J. of Urol. 150:100-105; 1993. 2. Lilja H, Christensson A, Dahlen U, et al. Prostate-specific antigen in serum occurs predominantly in complex with a-1-antichymotrypsin. Clin Chem 37:1618-1625, 1991. 3. Stenman U-H, Leinonen J, Alfthan H, Rannikko S, Tuhkanen K, Alfthan O. A complex between prostate-specific antigen and a-1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostate cancer: assay of the complex improves clinical sensitivity for cancer. Cancer Res. 51:222-226, 1991. 4. Catalona WJ, Smith DS, Ratliff TL, Basler JW. Detection of organ-confined prostate cancer is increased through prostate-specific antigen-based screening. JAMA. 270:948-954, 1993. 5. Stamey TA, Yang N Hay AR, McNeal JE, Freiha, FS, Redwine E. Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. N Engl J Med. 317-: 909-916, 1987.