Publications

25-OH Vitamin D ELISA

Calbiotech's 25-OH Vitamin D ELISA features 100% Cross-reactivity to D2 & D3 and no outside extraction step! This is a sensitive, robust and automation-friendly assay, requiring no external sample preparation and no organic solvents with a 2.5 hour total assay time. Clinical Significance Vitamin D is a steroid hormone involved...

Estimation of Estradiol in Mouse Serum Samples: Evaluation of Commercial Estradiol Immunoassays

Abstract The University of Virginia Center for Research in Reproduction Ligand Core performed an evaluation of nine commercial estradiol (E2) immunoassays for use with mouse serum. The evaluation had two components. 1) Recovery Studies: a mouse pool was spiked with E2 concentrations across the assay range, and percent recovery and...

Use of cotinine urinalysis to verify self-reported tobacco use among male psychiatric out-patients

Abstract Context: There is a complex and significant correlation between respiratory disorders and psychiatric conditions. Reliability of self-reported tobacco use has been questioned in recent times. Aims: The current study aims at assessment of accuracy of self-reported tobacco use (both smoked and smokeless) among psychiatric out-patients. Settings and Design: We...

Perfluorinated compounds are related to breast cancer risk in greenlandic inuit: A case control study

Abstract Background Breast cancer (BC) is the most common cancer for women in the western world. From very few cases an extraordinary increase in BC was observed in the Inuit population of Greenland and Canada although still lower than in western populations. Previous data suggest that exposure to persistent organic...

Arsenic exposure through drinking water increases the risk of liver and cardiovascular diseases in the population of West Bengal, India

Abstract Background Arsenic is a natural drinking water contaminant affecting 26 million people in West Bengal, India. Chronic arsenic exposure causes cancer, cardiovascular disease, liver disease, neuropathies and ocular diseases. The aims of the present study were to assess bioindicators of hepatocellular injury as indicated by the levels of liver...

4-Vinylcyclohexene Diepoxide (VCD) Inhibits Mammary Epithelial Differentiation and Induces Fibroadenoma Formation in Female Sprague Dawley Rats

Abstract 4-Vinylcyclohexene diepoxide (VCD), an occupational chemical that targets ovarian follicles and accelerates ovarian failure in rodents, was used to test the effect of early-onset reproductive senescence on mammary fibroadenoma formation. One-month female Sprague Dawley rats were dosed with VCD (80 mg/kg or 160 mg/kg) and monitored for 22 months...

Racial Differences in Paraoxonase-1 (PON1): A Factor in the Health of Southerners?

Abstract Background The southern United States (excluding Florida) has the highest age-adjusted rate of cardiovascular disease (CVD) in the country, with African Americans having a higher prevalence of CVD than Caucasians. Paraoxonase-1 (PON1), an enzyme associated with high-density lipoprotein particles, participates both in the hydrolysis of oxidized lipids (thus protecting...